Dr. Frasier Winslow Crane is a fictional character who is both a supporting character on the American television sitcom Cheers and the titular protagonist of its spin-off Frasier and the latter’s 2023 sequel. In all three series, he is portrayed by Kelsey Grammer. The character debuted in the Cheers third-season premiere, "Rebound (Part 1)" (1984), as Diane Chambers's love interest, part of the Sam and Diane story arc. Intended to appear for only a few episodes, Grammer's performance in the role was praised by producers, prompting them to expand his role and increase his prominence.

Later in Cheers, Frasier marries Lilith Sternin and has a son, Frederick. After Cheers ended, the character moved to a spin-off series, Frasier, through which the span of his overall television appearances totals twenty years. In the spin-off, Frasier moves back to his birthplace, Seattle, after his divorce from Lilith, who retained custody of Frederick.